Do you experience pain or numbness in your hand?

If so, you may be one of the millions of people suffering from carpal tunnel syndrome. We are now enrolling patients in a clinical study to compare the outcomes of carpal tunnel release with ultrasound guidance (CTR-US) and mini-open carpal tunnel release (mOCTR) in patients with symptomatic carpal tunnel syndrome.

Carpal Tunnel Symptom Tracker


  • Does pain in the wrist wake you up at night?
  • Does tingling and numbness in your hand wake you up at night?
  • Do you have or perform any trick movements to eliminate the tingling or numbness from your hands?
  • Do you have tingling and numbness in your little finger at any time?
  • Has tingling and numbness occurred when you were reading a newspaper, steering a car or knitting?
  • Do you have any neck pain?
  • Has the tingling and numbness in your hand been severe during pregnancy?
  • Has wearing a splint on your wrist helped the tingling and numbness?

If you answer yes to several of these questions, then your symptoms may be cause by carpal tunnel syndrome.


Study Locations

Sano Orthopedics Lee’s Summit office is 1 of 10 study locations. 


Carpal Tunnel Syndrome

Carpal Tunnel Syndrome is one of the most common causes of hand pain and numbness.

carpal tunnel wrist pain


Ready to schedule or have questions? Please fill out the form below. You can also text “Carpal Tunnel” to 816-551-2339 and we will contact you.

Sign up for a free diagnostic ultrasound carpal tunnel screening

November 11, 2022

Dr. Alexander Palmer will offer free diagnostic carpal tunnel screenings on November 11 at our Sano Orthopedics Lee’s Summit office. Reserve your spot today; appointments are limited.

Sign Up

Carpal Tunnel Release Clinical Study FAQs

What is a clinical study?

A clinical study is a type of medical research that compares one way of treating a patient with another. In this clinical study, the research is comparing the outcome of CTR-US and mOCTR.

Who is eligible?

You may be eligible to participate if:
– You are ≥18 years of age.
– You have a clinical diagnosis of carpal tunnel syndrome.
– Your symptoms have not improved with other treatment options including bracing, splinting or injections.
– Your physician considers you a surgical candidate.

Who is conducting the study?

-This clinical study is led by a physician (principal investigator) and includes physicians from a number of clinical sites across the United States.
-This clinical study is sponsored by Sonex Health, Inc. under an IRB approved study protocol number 20222668 and ClinicalTrials.gov Identifier: NCT05405218.

Why participate in a clinical study?

Surgical treatment may help; please discuss this with your physician.
– Carpal tunnel release procedures have been performed for almost 100 years.
– Procedural approaches and techniques have improved over time.
– The goal of any carpal tunnel surgery is to relieve pressure on the median nerve by dividing a ligament in your hand
– The purpose of this study is to compare the safety and effectiveness of CTR-US and mOCTR in patients with symptomatic carpal tunnel syndrome.
– CTR-US and mOCTR are two different techniques for carpal tunnel surgery and both relieve pressure on the median nerve by dividing a ligament in your hand.
– Study participants will be randomly assigned to one of two treatments: carpal tunnel release with ultrasound guidance or mini-open carpal tunnel release.

Will I be paid to join the study?

If you qualify for the study, you will be paid up to $300 to share your experiences during 6 follow-up time periods after the procedure.

How does the study work?

A series of tests and questionnaires will be given to you to verify if you meet the criteria to be a part of the study. This is called screening and will be done before you are randomized to a treatment group.
– Your physician will evaluate and discuss with you whether surgery is indicated to help the problem.
– If surgery is indicated, your physician will discuss whether you are eligible for this study.
– If you qualify to be in the study, you will be randomly assigned (by chance, like flipping a coin) to one of the two groups: the CTR-US Group or the mOCTR Group.


Regenerative medicine is an emerging area with ongoing research.  As such, regenerative treatments are still considered investigational and are not covered by insurance.  PRP and BMAC are not recommended for all patients or conditions. Set up an appointment with our Regenerative Medicine specialist to see if regenerative medicine may be right for you.


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